Focal limbal stem cell deficiency corresponding to an iris coloboma.

نویسندگان

  • E M Espana
  • V K Raju
  • S C G Tseng
چکیده

When the stem cells population is destroyed or their supporting stromal environment is dysfunctional, limbal stem cell deficiency (LSCD) manifests. Clinically, LSCD carries the hallmark of conjunctivalisation— that is, the corneal surface is covered by ingrowing conjunctival epithelium containing goblet cells. Conjunctivalisation is invariably associated with the destruction of the basement membrane, emergence of superficial neovascularisation, scarring, and diminished visual acuity.

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عنوان ژورنال:
  • The British journal of ophthalmology

دوره 86 12  شماره 

صفحات  -

تاریخ انتشار 2002